V. Hampl: Abstracts

1. Jakoubek V., Bíbová J., Venclíková K., Hampl V.: Chronic hypoxia elevates fetoplacental vascular resistance. FASEB Journal in press, 2006.

2. Lachmannová V., Bíbová J., Miková D., Hniličková O., Hampl V.: Nitric oxide production into the exhaled air is elevated by 4 days of hypoxia in the lower, but not the upper, respiratory tract. Physiological Research 54: 1P, 2005.

3. Hodyc D., Hniličková O., Hampl V., Herget J.: Pre-arrest administration of cell permeable ROS scavenger – tempol, reduces warm ischemic damage of lung function in non-heart-beating donors. Journal of Physiology in press, 2005.

4. Hodyc D., Hnilicková O., Hampl V., Herget J.: Heparinization but not ventilation during warm ischemia improves lung function in non-heart-beating donors. FASEB Journal in press, 2005.

5. Herget J., Vajner L., Hampl V.: Collagenase expressing mast cells accummulate in walls of peripheral pulmonary arteries in the initiation of hypoxic pulmonary hypertension. Journal of Physiology in press, 2005.

6. Bíbová J., Hniličková O., Hampl V., Herget J.: Perinatal hypoxia aggravates pulmonary hypertension in adulthood. FASEB Journal, 2005.

7. Bíbová J., Chalupský K., Hojná S., Hrdličková A., Hampl V.: Hypoxia reduces eNOS expression in hypoxic rat placentas. Physiological Research: in press, 2005.

8. Kunes J., Miková D., Dobesová Z., Bíbová J., Hampl V., Zicha J.: Vasodilatory mechanisms in L-NAME hypertension. Hypertension 44: 566, 2004.

9. Hampl V., Lachmanová V., Hniličková O., Herget J.: Critical role of oxygen radicals in the early phase of hypoxic pulmonary hypertension development. FASEB Journal 18: A1056, 2004.

10. Bobková D., Miková D., Hampl V., Kovář J., Poledne R.: NO production in an experimental model of hyperlipoproteinemia - apolipoprotein E-defficient mice. Physiological Research 53: 2P, 2004.

11. Bíbová J., Hniličková O., Hampl V., Herget J.: Perinatal hypoxia results in increase of pulmonary vascular reactivity to hypoxic exposure in adult rats. Physiological Research in press, 2004.

12. Bíbová J., Baňasová A., Miková D., Hampl V., Herget J.: Inducible nitric oxide synthase particicates in the mechanism of hypoxic pulmonary hypertension. Physiological Research 53: 2P, 2004.

13. Bíbová J., Baňasová A., Herget J., Hampl V.: Slowly reversible normalization of blood pressure by 2-week hypoxia in the ren-2 transgenic rat model of hypertension. Physiological Research 53: 1P, 2004.

14. Baňasová A., Bíbová J., Miková D., Herget J., Hampl V.: Chronic hypoxia alters nitric oxide in exhaled breath: newborn rats differ from adults. Physiological Research 53: 1P, 2004.

15. Kolár F., Szárszoi O., Neckár J., Pechánová O., Miková D., Hampl V., Ostádal B.: Role of nitric oxide and reactive oxygen species in reperfusion-induced arrhytmias and cardioprotection in chronically hypoxic rat hearts. Physiological Research 52: 52P, 2003.

16. Bíbová J., Miková D., Baňasová A., Herget J., Hampl V.: Time profile of breath NO release during three week hypoxia. Physiological Research 52: 24P, 2003.

17. Bíbová J., Miková D., Baňasová A., Herget J., Hampl V.: Inducible nitric oxide synthase contributes to the development of chronic hypoxic pulmonary hypertension. FASEB Journal 17: A408, 2003.

18. Banasová A., Bíbová J., Hampl V.: Gender difference in pulmonary vascular handling of intracellular calcium is abolished by orchiectomy. Physiological Research 52: 23P, 2003.

19. Zlámal M., Hodyc D., Hampl V., Herget J.: Increase in the pulmonary vascular tonus induced by 4 days of hypoxia is located in arterial vascular segment. Physiological Research 51: 54P, 2002.

20. Herget J., Hampl V., Novotná J., Fišárková B., Vytášek R., Veselá A., Wilhelm J.: Inhibition of radical tissue injury by hypercapnia attenuates the development of hypoxic pulmonary hypertension (HPH) in rats. Nitric Oxide: Biology and Chemistry 6: 400-401, 2002.

21. Hampl V., Bíbová J., Miková D., Baňasová A., Herget J.: Prolonged, selective inhibition of inducible nitric oxide synthase (iNOS) in intact rats by addition of L-N6-(1-iminoethyl)lysine (L-NIL) to drinking water. Nitric Oxide: Biology and Chemistry 6: 398-399, 2002.

22. Bíbová J., Ošťádalová I., Herget J., Hampl V.: Sex hormones determine the permanent effects of perinatal hypoxia on the pulmonary circulation. Physiological Research 51: 65P, 2002.

23. Bíbová J., Miková D., Baňasová A., Hampl V., Herget J.: Inducible nitric oxide synthase participates in the mechanism of chronic hypoxic pulmonary hypertension. Physiological Research 51: 71P, 2002.

24. Bíbová J., Hampl V.: Calcium-gated potassium (KCa) channels participate in the mechanism of hypoxic fetoplacental vasoconstriction. FASEB Journal 16: A62, 2002.

25. Bíbová J., Hampl V.: Hypoxic fetoplacental vasoconstriction is mediated by reduced activity of potassium channels. Physiological Research 51: 3P, 2002.

26. Banasová A., Bíbová J., Hampl V.: Gender differences in the role of calcium release from sarcoplasmic reticulum in the pulmonary vascular tone regulation. Physiological Research 51: 71P, 2002.

27. Herget J., Vytášek R., Baňasová A., Bíbová J., Hampl V., Fišárková B.: Hypercapnia inhibits hypoxic pulmonary hypertension in rats. Physiological Research 50: P7, 2001.

28. Herget J., Novotná J., Wilhelm J., Hampl V.: Hypoxická plicní hypertenze: interakce pozitivních a negativních pÛsobení. Cor et Vasa 43: 23, 2001.

29. Hampl V., Bíbová J., Herget J.: Long term effects of perinatal hypoxia on the pulmonary circulation. FASEB Journal 15: A816, 2001.

30. Bíbová J., Herget J., Hampl V.: The role of inducible nitric oxide synthase in the mechanism of chronic hypoxic pulmonary hypertension. Physiological Research 50: P35, 2001.

31. Banasová A., Bíbová J., Hampl V.: Pulmonary vasoconstriction-induced nitric oxide (NO) synthesis depends on calcium release from endoplasmic reticulum (ER). Physiological Research 50: P35, 2001.

32. Banasová A., Bíbová J., Hampl V.: Sarcoplasmic reticulum calcium pump participates in the mechanism of hypoxic pulmonary vasoconstriction. Physiological Research 50: P1, 2001.

33. Novotná J., Herget J., Bíbová J., Hampl V.: Suppression of hypoxic pulmonary hypertension by the inhibitor of collagenolytic activity (Batimastat) in rats. Physiological Research 49: P12, 2000.

34. Michelakis E.D., Hampl V., Sun X.-J., Weir K.E., Archer S.L.: Mitochondrial diversity and vascular oxygen sensing. Circulation 102: II-101, 2000.

35. Michelakis E.D., Hampl V., Sun X., Archer S.L.: Differences in mitochondrial function may explain the opposite responses of the pulmonary and renal arteries to acute hypoxia. Canadian Journal of Cardiology 16: 117F, 2000.

36. Michelakis E., Hampl V., London B., Archer S.: Hypoxic pulmonary vasoconstriction is diminished in a mouse lacking Kv1.5 channels. FASEB Journal 14: A108, 2000.

37. Kwong S., Archer S., Hampl V., Puttagunta L., Hashimoto K., Michelakis E.: Inward rectifier potassium channels in the pulmonary circulation. American Journal of Respiratory and Critical Care Medicine 161: I-234, 2000.

38. Herget J., Bíbová J., Hampl V.: Late effects of perinatal hypoxia on pulmonary vessels are gender dependent. Experimental and Clinical Cardiology 5: 39, 2000.

39. Hampl V., Bíbová J., Straňák Z.: Hypoxia causes vasoconstriction in the fetoplacental vascular bed. Physiological Research 49: P8, 2000.

40. Hampl V., Bíbová J., Straňák Z.: Hypoxic vasoconstriction in the fetoplacental vascular bed. Experimental and Clinical Cardiology 5: 39, 2000.

41. Hampl V., Bíbová J., Ošťádalová I., Herget J.: Ovaries protect adult female rats born in hypoxia from the development of pulmonary hypertension. FASEB Journal 14: A125, 2000.

42. Hampl V.: Pulmonary hypertension is not caused by nitric oxide defficiency. Physiological Research 49: 3P, 2000.

43. Bíbová J., Herget J., Hampl V.: Calcium gated potassium channel activator, dehydroepiandrosterone sulfate, reduces hypoxic pulmonary hypertension in rats. Physiological Research 49: P7, 2000.

44. Bíbová J., Herget J., Hampl V.: Activation of calcium gated potassium channels reduces hypoxic pulmonary hypertension in rats. FASEB Journal submitted, 2000.

45. Novotná J., Herget J., Bíbová J., Hampl V.: Inhibitior of collagenolytic activity suppresses hypoxic pulmonary hypertension in rats. Physiological Research 48: 45P, 1999.

46. Herget J., Novotná J., Bíbová J., Hampl V., Povýšilová V.: Hypoxic pulmonary hypertension in rats is inhibited by anti-oxidant, N-acetyl cysteine. Physiological Research 48: 54P, 1999.

47. Hampl V., Bíbová J., Herget J.: Long-term effects of perinatal hypoxia on the pulmonary circulation: are they protective? Physiological Research 48: 56P, 1999.

48. Bíbová J., Hampl V.: Selective blockade of the calcium pump of the sarcoplasmic reticulum inhibits hypoxic vasoconstriction in isolated rat lungs. Physiological Research 48: 51P, 1999.

49. Belohlávková S., ·imák J., Hniliãková O., Koke‰ová A., Hampl V.: Fenfluramine-induced vasoconstriction in isolated rat lungs is reduced by a 5-hydroxytryptamine/2+1C receptor antagonist ritanserin. Physiological Research 48: 40P, 1999.

50. Archer S.L., Michelakis E.M., London B., Hampl V.: Role of voltage-gated potassium channels Kv1.5, Kv1.2 and Kv2.1 in the control of hypoxic pulmonary vasoconstriction. Physiological Research 48: 48P, 1999.

51. Kucera T., Laude E., Hampl V.: The appetite suppressant, fenfluramine, causes contraction of precontracted, small pulmonary arteries of the rat in vitro. Journal of Physiology 511: 116P, 1998.

52. Herget J., Novotná J., Hampl V., Bíbová J.: Chronic moderate hyperoxia does not result in pulmonary hypertension in rats. Journal of Physiology 511: 117P-118P, 1998.

53. Herget J., Bíbová J., Hampl V.: Antioxidant N-acetylcysteine inhibits development of hypoxic pulmonary hypertension in rats. Journal of Vascular Research 35: 5, 1998.

54. Hampl V., Nelson D.P., Archer S.L.: Antibodies against the Kv1.5 voltage-gated potassium channel inhibit hypoxic pulmonary vasoconstriction. Physiological Research 65: P28, 1997.

55. Dinh-Xuan A.T., Souil E., Hampl V., Nguyen-Huu L., Dall'Ava-Santucci J., Archer S.L.: Rôles physioloques des canaux potassiques réglés par le voltage dans la vasoconstriction pulmonaire hypoxique. Archives of Physiology and Biochemistry 105: 306, 1997.

56. Tristani-Firouzi M., Hampl V., Archer S.L.: Aerosolized NONOates reduce hypoxic pulmonary vasoconstriction in the isolated, perfused rat lung. Circulation 92: I-700, 1995.

57. Hampl V., Huang J.M.C., Weir E.K., Archer S.L.: Nitric oxide activates Ca-sensitive K channels. American Journal of Respiratory and Critical Care Medicine 151: A527, 1995.

58. Hampl V., Cowan N.J., Archer S.L.: Acute hypoxia increases nitric oxide synthesis in cultured pulmonary arterial cells. American Journal of Respiratory and Critical Care Medicine 151: A627, 1995.

59. Archer S.L., Reeve H.L., Hampl V., Huang J., Peterson D.A., Weir E.K.: Redox regulation of pulmonary vascular tone: a central role for potassium channels. Journal of Physiology 487.P: 11S-12S, 1995.

60. Archer S.L., Hampl V., Reeve H.L., Huang J.M.C., Tolarová S., Michelakis E., Weir E.K.: Regional diversity of vascular myocyte K channel types between conduit and resistance arteries explains vascular reactivity to hypoxia and nitric oxide. Circulation 92: I-635-I-636, 1995.

61. Hampl V., Weir E.K., Archer S.L.: Long-term nitric oxide (NO) infusion in rats with pulmonary hypertension. FASEB Journal 8: A531, 1994.

62. Hampl V., Huang J., Nelson D.P., Weir E.K., Archer S.L.: Cyclic guanosine monophosphate and nitric oxide relax rat pulmonary vascular smooth muscle by activating a charybdotoxin sensitive K current. American Journal of Respiratory and Critical Care Medicine 149: A292, 1994.

63. Archer S.L., Huang J., Nelson D.P., Hampl V., Weir E.K.: Activation of a calcium sensitive K channel by nitric oxide is dependent on a cyclic nucleotide-dependent kinase in rat pulmonary vascular smooth muscle cells. American Journal of Respiratory and Critical Care Medicine 149: A292, 1994.

64. Archer S.L., Hampl V., Nelson D., Weir E.K.: Inhibitors of sarcoplasmic reticulum release and reuptake attenuate several types of pulmonary vasoconstriction in isolated rat lungs. Circulation 90: I-151, 1994.

65. Archer S.L., Hampl V., Nelson D., Sidney E., Weir E.K.: Dithionite causes dose dependent inhibition of pulmonary vasoconstriction and does not mimic hypoxia in the isolated rat lungs. Circulation 90: I-151, 1994.

66. Archer S.L., Hampl V., Nelson D., Huang J., Tolarová S., Shultz P.J., Weir E.K.: Forskolin-induced vasodilation is not attenuated by K channel blockers or cyclic nucleotide-dependent kinase inhibitors in the rat pulmonary artery. Circulation 90: I-148, 1994.

67. Hampl V., Weir E.K., Archer S.L.: EDRF modulates basal and flow-induced tone in isolated kidneys, but not lungs, of adult rats. American Review of Respiratory Diseases 147: A225, 1993.

68. Hampl V., Archer S.L., Bach R., Nelson D.P., Weir E.K.: Hirudin does not significantly prevent chronic hypoxic pulmonary hypertension in rats. American Review of Respiratory Diseases 147: A494, 1993.

69. Archer S.L., Hampl V., Nelson D.P., Weir E.K.: Pulmonary nitric oxide synthesis and vasoconstriction to Nw-nitro-L-arginine methyl ester are enhanced in chronic hypoxic pulmonary hypertension. Circulation 88: I-285, 1993.

70. Isaacson T., Weir E.K., Hampl V., Nelson D., Archer S.: Enhanced vasoconstriction in chronic hypoxic pulmonary hypertension is not associated with reduced responsiveness to EDRF or nitric oxide. FASEB Journal 6: A1177, 1992.

71. Herget J., Hampl V., Brunner C.: Effect of papaverine on P/Q relationship in control and hypoxic rats. European Respiratory Journal 5: 90s, 1992.

72. Hampl V., Herget J., Povýšilová V., Slavík Z.: Effect of prenatal treatment with indomethacin on pulmonary blood vessels in the rat. European Respiratory Journal 4: 371s-372s, 1991.

73. Slavík Z., Hampl V., Herget J.: Effect of experimental polycythaemia on pulmonary circulation in the rat. Physiologia bohemoslovaca 39: 267, 1990.

74. Hampl V., Herget J.: Pulmonary vascular reactivity in rats with genetic systemic hypertension. European Respiratory Journal 3: 366s, 1990.

75. Hampl V., Slavík Z., Herget J.: Prenatal indomethacin treatment alters hypoxic pulmonary vasoconstriction in adult rats. Physiologia bohemoslovaca 38: 534, 1989.

76. Hampl V., Herget J.: Mechanical properties of the rat pulmonary vascular bed are influenced by perinatal hypoxia. Physiologia bohemoslovaca 38: 374, 1989.

77. Hampl V., Herget J.: Effects of perinatal hypoxia on pulmonary hypoxic vascular reactivity in adult rats. Physiologia bohemoslovaca 37: 382, 1988.

78. Herget J., Hampl V., Paleček F.: Effect of perinatal hypoxia on hypoxic vascular reactivity in adult rats. Atemwegs- and Lungenkrankheten 13: 132, 1987.

79. Hampl V., Mejsnar J.: Thermogenic effect of noradrenaline in skeletal muscle perfused in vitro. Physiologia bohemoslovaca 35: 353-354, 1986.