PRL - prolactin
cause milk secretion from the breast after estrogen and progesterone priming after delivery
preventing ovulatin in lacting women
females - blockage of the action of gonadotropins on the ovaries (20 % secondary amenorrhea, infertility, risk of osteoporosis due to estrogen deficiency)
males - impotence and hypogonadism
70 % patients with chromophobe adenomas of the anterior pituitary (prolactinoma)