Nondisjunction of the sex chromosomes during gametogenesis

• Turner syndrome

gonadal dysgenesis, ovarian agenesis (XO and variants)

44 XX _ 22 0 _ 44 X0 _ 22 X

44 XX _ 22 X _ 44 X0 _ 22 0

(80 % loss of parental X)

the gonads are rudimentary or absent

female external genitalia develops

no sexual maturity during adolescence

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